Age mosaic of gut epithelial cells prevents aging

Abstract Improving gut health by altering the activity of intestinal stem cells is thought to have the potential to reverse aging. The aged Drosophila midgut undergoes hyperplasia and barrier dysfunction. However, it is still unclear how to limit hyperplasia to extend lifespan. Here, we show that ea...

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Bibliographic Details
Main Authors: Peizhong Qin, Qi Wang, You Wu, Qiqi You, Mingyu Li, Zheng Guo
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62043-y
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