Microhomology-mediated end-joining Knock-In approaches to delete the allergenic domain of trout parvalbumin beta-1. Preliminary results in F0 animals and feedback [version 2; peer review: 1 approved, 2 approved with reservations]

Background Gene editing techniques offer new opportunities to improve important traits in aquaculture. The allergenicity of fish flesh is a major problem in aquaculture. Parvalbumin (Parv) is the most prevalent fish allergen. For instance, in salmonids, a single parvalbumin beta-1 protein (parvb1) h...

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Bibliographic Details
Main Authors: Amaury Herpin, Cecile Duret, Pierre-yves Rescan, Veronique Lebret
Format: Article
Language:English
Published: F1000 Research Ltd 2025-02-01
Series:Open Research Europe
Subjects:
Online Access:https://open-research-europe.ec.europa.eu/articles/4-235/v2
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