Revealing pathogenesis-associated metabolites in Histoplasma capsulatum through comprehensive metabolic profiling

ABSTRACT During infection, Histoplasma capsulatum yeasts interact with a variety of phagocytic cells, where macrophages represent an important niche for long-term intracellular fungal survival and replication. In the phagosomes of macrophages, a hostile environment where most microorganisms are kill...

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Bibliographic Details
Main Authors: Adrian Heckart, Jean-Christophe Cocuron, Stephanie C. Ray, Chad A. Rappleye, Ana P. Alonso
Format: Article
Language:English
Published: American Society for Microbiology 2025-03-01
Series:mSystems
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/msystems.00186-25
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