Impact on parasitemia, survival time and pro-inflammatory immune response in mice infected with Plasmodium berghei treated with Eleutherine plicata

Impact on parasitemia, survival time and pro-inflammatory immune response in mice infected with Plasmodium berghei treated with Eleutherine plicata

In vitro studies with Plasmodium falciparum have demonstrated the antiparasitic activity of E. plicata, attributed to its naphthoquinones. This study reports on pro-inflammatory changes in mice infected with P. berghei and correlates these changes with parasitemia and survival. The ethanol extract o...

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Main Authors: Antônio Rafael Quadros Gomes, Ana Laura Gadelha Castro, Gleison Gonçalves Ferreira, Heliton Patrick Cordovil Brígido, Everton Luiz Pompeu Varela, Valdicley Vieira Vale, Liliane Almeida Carneiro, Maria Fâni Dolabela, Sandro Percario
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Pharmacology
Subjects:
eleutherol
eleutherol glucuronide
isoeleutherin
eleutherin
malaria
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1484934/full
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https://www.frontiersin.org/articles/10.3389/fphar.2024.1484934/full

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