Adjuvant Wilms’ tumour 1-specific dendritic cell immunotherapy complementing conventional therapy for paediatric patients with high-grade glioma and diffuse intrinsic pontine glioma: protocol of a monocentric phase I/II clinical trial in Belgium

Adjuvant Wilms’ tumour 1-specific dendritic cell immunotherapy complementing conventional therapy for paediatric patients with high-grade glioma and diffuse intrinsic pontine glioma: protocol of a monocentric phase I/II clinical trial in Belgium

Introduction Diffuse intrinsic pontine glioma (DIPG) and paediatric high-grade glioma (pHGG) are aggressive glial tumours, for which conventional treatment modalities fall short. Dendritic cell (DC)-based immunotherapy is being investigated as a promising and safe adjuvant therapy. The Wilms’ tumour...

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Main Authors: Stijn Verhulst, Sven Dekeyzer, Griet Nijs, Maxime De Laere, Marie-Madeleine Couttenye, Zwi Berneman, Nathalie Cools, Manon Huizing, Ella Roelant, Toon Van Genechten, Jolien Van den Bossche, Barbara Stein, kim De Rycke, Caroline Deschepper, Katja Hazes, Renke Peeters, Katrien Van De Walle, Sabine Maes, Stephanie Vanden Bossche, Kim Caluwaert, Joris Verlooy, Koen Norga, Sebastien Anguille, Eva Lion
Format: Article
Language:English
Published: BMJ Publishing Group 2024-03-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/14/3/e077613.full
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https://bmjopen.bmj.com/content/14/3/e077613.full

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