Stem-Cell Niches in Health and Disease: Microenvironmental Determinants of Regeneration and Pathology

Stem-cell behavior is governed not solely by intrinsic genetic programs but by highly specialized microenvironments—or niches—that integrate structural, biochemical, and mechanical cues to regulate quiescence, self-renewal, and differentiation. This review traces the evolution of stem-cell niche bio...

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Bibliographic Details
Main Authors: Boris Yushkov, Valerii Chereshnev, Elena Korneva, Victoria Yushkova, Alexey Sarapultsev
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/14/13/981
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