[225Ac]Ac-PSMA-617 production method: development of an efficient and reproducible radiolabelling process for establish a clinical routine production

[225Ac]Ac-PSMA-617 production method: development of an efficient and reproducible radiolabelling process for establish a clinical routine production

Abstract Background Targeted Alpha Therapy shows very promising clinical results in a cancer treatment and it should be comparable or better than chemotherapy and β-radionuclide therapy, in terms of efficacy and toxicity. The use of α-emission offers advantages over β-emission due to the high linear...

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Bibliographic Details
Main Authors: Michela Aurilio, Aureliana Esposito, Monica Buonanno, Anna Morisco, Costantina Maisto, Stefania Scala, Secondo Lastoria
Format: Article
Language:English
Published: SpringerOpen 2025-05-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Actinium-225
PSMA-617
Prostate cancer
PCa
RCY
RCP
Online Access:https://doi.org/10.1186/s41181-025-00344-9
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https://doi.org/10.1186/s41181-025-00344-9

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