Interethnic differences in single and haplotype structures of folylpolyglutamate synthase and gamma-glutamyl hydrolase variants and their influence on disease susceptibility to acute lymphoblastic leukemia in the Indian population: An exploratory study

Interethnic differences in single and haplotype structures of folylpolyglutamate synthase and gamma-glutamyl hydrolase variants and their influence on disease susceptibility to acute lymphoblastic leukemia in the Indian population: An exploratory study

Aim: We aim to establish the genotype and haplotype frequencies of folylpolyglutamate synthase (FPGS rs10106 and rs1544105) and gamma-glutamyl hydrolase (GGH rs3758149 and rs11545078) variants in the South Indian population (SI) and to study the association of these variants with susceptibility to a...

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Bibliographic Details
Main Authors: Sunitha Kodidela, Suresh Chandra Pradhan, Biswajit Dubashi, Debdatta Basu
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2018-01-01
Series:Indian Journal of Medical and Paediatric Oncology
Subjects:
Antifolates
folate
folylpolyglutamate synthase
gamma-glutamyl hydrolase
haplotypes
polymorphism
Online Access:http://www.ijmpo.org/article.asp?issn=0971-5851;year=2018;volume=39;issue=3;spage=331;epage=338;aulast=Kodidela
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http://www.ijmpo.org/article.asp?issn=0971-5851;year=2018;volume=39;issue=3;spage=331;epage=338;aulast=Kodidela

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