Neuronal p38 MAPK Signaling Contributes to Cisplatin-Induced Peripheral Neuropathy

Neuronal p38 MAPK Signaling Contributes to Cisplatin-Induced Peripheral Neuropathy

This study investigates the role of p38 mitogen-activated protein kinase (MAPK) activation in dorsal root ganglion (DRG) neurons in the development and progression of chemotherapy-induced peripheral neuropathy (CIPN). This research evaluates whether inhibiting activation of p38 MAPK could reduce neu...

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Bibliographic Details
Main Authors: Yugal Goel, Donovan A. Argueta, Kristen Peterson, Naomi Lomeli, Daniela A. Bota, Kalpna Gupta
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Antioxidants
Subjects:
cancer
cisplatin
CIPN
dorsal root ganglion
neuron
pain
Online Access:https://www.mdpi.com/2076-3921/14/4/445
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