Genomic epidemiology and characterization of difficult-to-treat resistant Pseudomonas aeruginosa isolates co-harboring bla OXA-50 and crpP causing bronchiectasis

Genomic epidemiology and characterization of difficult-to-treat resistant Pseudomonas aeruginosa isolates co-harboring bla OXA-50 and crpP causing bronchiectasis

Abstract Difficult-to-treat resistant Pseudomonas aeruginosa (DTR-PA) is an MDR subset resistant to all first-line antipseudomonal agents. It is particularly concerning in respiratory infections like bronchiectasis, leading to poor outcomes, limited treatment options, and higher healthcare costs. Th...

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Bibliographic Details
Main Authors: Lulu Jin, Haowei Ye, Hao Xu, Amina shahzadi, Xinling Pan, Danfeng Lou
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Pseudomonas aeruginosa
bla OXA-50
crpP
Difficult-to-treat resistance (DTR-PA)
Online Access:https://doi.org/10.1038/s41598-025-95950-7
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https://doi.org/10.1038/s41598-025-95950-7

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