Benchmarking single-cell cross-omics imputation methods for surface protein expression

Abstract Background Recent advances in single-cell multimodal omics sequencing have facilitated the simultaneous profiling of transcriptomes and surface proteomes within individual cells, offering insights into cellular functions and heterogeneity. However, the high costs and technical complexity of...

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Bibliographic Details
Main Authors: Chen-Yang Li, Yong-Jia Hong, Bo Li, Xiao-Fei Zhang
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Genome Biology
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Online Access:https://doi.org/10.1186/s13059-025-03514-9
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