Predicting phage-host interaction via hyperbolic Poincaré graph embedding and large-scale protein language technique

Predicting phage-host interaction via hyperbolic Poincaré graph embedding and large-scale protein language technique

Summary: Bacteriophages (phages) are increasingly viewed as a promising alternative for the treatment of antibiotic-resistant bacterial infections. However, the diversity of host ranges complicates the identification of target phages. Existing computational tools often fail to accurately identify ph...

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Bibliographic Details
Main Authors: Jie Pan, Rui Wang, Wenjing Liu, Li Wang, Zhuhong You, Yuechao Li, Zhemeng Duan, Qinghua Huang, Jie Feng, Yanmei Sun, Shiwei Wang
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:iScience
Subjects:
Virology
Microbiology
Bacteriology
Machine learning
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224028748
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