Discovery, structural characteristics and evolutionary analyses of functional domains in Acinetobacter baumannii phage tail fiber/spike proteins

Discovery, structural characteristics and evolutionary analyses of functional domains in Acinetobacter baumannii phage tail fiber/spike proteins

Abstract Background The global rise in multidrug-resistant Acinetobacter baumannii infections poses a significant healthcare challenge. Bacteriophage offer a promising alternative to antibiotics for treating A. baumannii infections. Phage tail fiber and spike proteins are essential for host recognit...

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Bibliographic Details
Main Authors: Shenshen Liu, Tao Lei, Yujing Tan, Xiaoyi Huang, Wenxin Zhao, Huanhuan Zou, Jianhui Su, Ji Zeng, Haiyan Zeng
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Microbiology
Subjects:
Acinetobacter baumannii
Phage
Tail fiber
Tail spike
Depolymerase
Pectin lyase-like
Online Access:https://doi.org/10.1186/s12866-025-03790-2
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https://doi.org/10.1186/s12866-025-03790-2

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