Anxiolysis for laceration repair in children: statistical analysis plan for an open-label multicenter adaptive trial (ALICE)

Anxiolysis for laceration repair in children: statistical analysis plan for an open-label multicenter adaptive trial (ALICE)

Abstract Background Laceration repairs are a common, yet distressing procedure in children. While a range of strategies is used to treat this distress, there is currently no standard of care. The Anxiolysis for Laceration Repair in Children (ALICE) trial aims to identify the most effective pharmacol...

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Bibliographic Details
Main Authors: Arlene Jiang, Naveen Poonai, Vinolia Arthur-Hayward, Anna Heath
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Trials
Subjects:
Statistical analysis plan
Bayesian clinical trial
Procedural pain
“Probability of being best”-statistic
SUCRA
Online Access:https://doi.org/10.1186/s13063-025-09009-z
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https://doi.org/10.1186/s13063-025-09009-z

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