Development of a LC–MS/MS analytical method of 15 compounds related to renal function for a prognostic method of progression risk in patients with diabetic kidney disease

Development of a LC–MS/MS analytical method of 15 compounds related to renal function for a prognostic method of progression risk in patients with diabetic kidney disease

Diabetic kidney disease (DKD) onset and progression is a major cause of end-stage renal failure in diabetic patients, however, no practical method has been reported to predict the progression rate of renal function decline. Nine serum compounds are reported to associate with prognosis in type 1 diab...

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Bibliographic Details
Main Authors: Ryota Kujirai, Yotaro Matsumoto, Mizuki Abe, Kodai Hiramoto, Takumi Watanabe, Chitose Suzuki, Takafumi Toyohara, Takaaki Abe, Yoshihisa Tomioka
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Journal of Pharmaceutical and Biomedical Analysis Open
Subjects:
Diabetic kidney disease
Progressive renal decline
Stable isotope-labeled internal standard
Validation
LC–MS/MS
Online Access:http://www.sciencedirect.com/science/article/pii/S2949771X2300021X
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