Efficacy and safety of the metformin-mazindol anorectic combination in rat

Efficacy and safety of the metformin-mazindol anorectic combination in rat

The current study investigates the anorectic interaction and safety of the mazindol-metformin combination in rats. Isobologram and interaction index were used to determine anorectic interaction between mazindol and metformin in the sweetened milk model. The safety profile of the mazindol-metformin c...

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Main Authors: Argüelles-Tello Federico, Roa-Coria José Eduardo, Zúñiga-Romero Ángel, Huerta-Cruz Juan Carlos, Quiñonez-Bastidas Geovanna Nalley, Flores-Murrieta Francisco Javier, Rocha-González Héctor Isaac, Reyes-García Juan Gerardo
Format: Article
Language:English
Published: Sciendo 2021-06-01
Series:Acta Pharmaceutica
Subjects:
mazindol-metformin combination
anorectic interaction
anxiolysis
hypoglycemic effect
Online Access:https://doi.org/10.2478/acph-2021-0019
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https://doi.org/10.2478/acph-2021-0019

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