Structures and functions of the MICOS: Pathogenesis and therapeutic implications in Alzheimer's disease

Mitochondrial dysfunction is a critical factor in the pathogenesis of Alzheimer's disease (AD). The mitochondrial contact site and cristae organizing system (MICOS) plays a pivotal role in shaping the inner mitochondrial membrane, forming cristae junctions and establishing interaction sites bet...

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Bibliographic Details
Main Authors: Zihan Wang, Kaige Zhang, Minghao Huang, Dehao Shang, Xiaomin He, Zhou Wu, Xu Yan, Xinwen Zhang
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221138352500276X
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