Monocytes regulate the mechanism of T-cell death by inducing Fas-mediated apoptosis during bacterial infection.

Monocytes regulate the mechanism of T-cell death by inducing Fas-mediated apoptosis during bacterial infection.

Monocytes and T-cells are critical to the host response to acute bacterial infection but monocytes are primarily viewed as amplifying the inflammatory signal. The mechanisms of cell death regulating T-cell numbers at sites of infection are incompletely characterized. T-cell death in cultures of peri...

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Bibliographic Details
Main Authors: Marc Daigneault, Thushan I De Silva, Martin A Bewley, Julie A Preston, Helen M Marriott, Andrea M Mitchell, Timothy J Mitchell, Robert C Read, Moira K B Whyte, David H Dockrell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002814&type=printable
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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002814&type=printable

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