Elucidation of short linear motif-based interactions of the MIT and rhodanese domains of the ubiquitin-specific protease 8
Abstract Ubiquitin-specific protease 8 (USP8) is a deubiquitinating enzyme with essential functions in protein trafficking and stability. It is a multidomain protein, with an N-terminal MIT (microtubule interacting and trafficking) domain, followed by a non-catalytic rhodanese (Rhod) domain, a long...
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| Main Authors: | Aimiliani Konstantinou, Julia K. Varga, Alicia Córdova-Pérez, Leandro Simonetti, Lidia Gomez-Lucas, Ora Schueler-Furman, Norman E. Davey, Yogesh Kulathu, Ylva Ivarsson |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-05-01
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| Series: | Biology Direct |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13062-025-00638-7 |
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