Genetic characterization of BRCA1 and BRCA2 variants in cancer and high-risk family screening cohorts in the UAE population

Genetic characterization of BRCA1 and BRCA2 variants in cancer and high-risk family screening cohorts in the UAE population

Abstract Introduction Germline BRCA1/2 (gBRCA1/2) variants are strongly associated with hereditary cancers, and screening for these variants in high-risk populations is recommended for personalized management. This study aims to comprehensively characterize gBRCA1/2 variants in cancer and family scr...

Full description

Saved in:
Bibliographic Details
Main Authors: Abeer Arif Abdalla Abutalib Al Ali, Moza Mohamed Alechleh Al Ali, Dalia Mahmoud Abdel-Hamid El-Shourbagy, Syed Hammad Hassan Tirmazy, Imran Mirza, Afsheen Raza, Muhammad Farooq Latif, Hemad Yasaei
Format: Article
Language:English
Published: Springer 2025-04-01
Series:Journal of Cancer Research and Clinical Oncology
Subjects:
BRCA1, BRCA2
Breast cancer, ovarian cancer
Prostate cancer
Pancreatic cancer
Prevalence
United Arab Emirates
Online Access:https://doi.org/10.1007/s00432-025-06188-9
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1007/s00432-025-06188-9

Similar Items