Myeloid-derived suppressor cell inhibits T-cell-based defense against Klebsiella pneumoniae infection via IDO1 production.

Klebsiella pneumoniae (Kp) is responsible for a wide range of infections, including pneumonia, sepsis, and urinary tract infections. However, the treatment options are limited due to the continuous evolution of drug-resistant and hypervirulent variants. It is crucial to investigate the mechanisms be...

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Bibliographic Details
Main Authors: Qi Xu, Xiaoxuan Liu, Heng Heng, Han Wang, Kaichao Chen, Edward Wai-Chi Chan, Guan Yang, Sheng Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-03-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012979
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