Ketamine Boluses Are Associated with a Reduction in Intracranial Pressure and an Increase in Cerebral Perfusion Pressure: A Retrospective Observational Study of Patients with Severe Traumatic Brain Injury

Ketamine Boluses Are Associated with a Reduction in Intracranial Pressure and an Increase in Cerebral Perfusion Pressure: A Retrospective Observational Study of Patients with Severe Traumatic Brain Injury

Background. Increased intracranial pressure (ICP) and hypotension have long been shown to lead to worse outcomes in the severe traumatic brain injury (TBI) population. Adequate sedation is a fundamental principle in TBI care, and ketamine is an attractive option for sedation since it does not common...

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Main Authors: Bradley A. Dengler, Oliver Karam, Colleen A. Barthol, Aaron Chance, Laura E. Snider, Clare M. Mundy, Michael T. Bounajem, William C. Johnson, Moustafa M. Maita, Paola M. Mendez-Gomez, Ali Seifi, Shaheryar Hafeez
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Critical Care Research and Practice
Online Access:http://dx.doi.org/10.1155/2022/3834165
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