The Manufacture of GMP-Grade Bone Marrow Stromal Cells with Validated In Vivo Bone-Forming Potential in an Orthopedic Clinical Center in Brazil

The Manufacture of GMP-Grade Bone Marrow Stromal Cells with Validated In Vivo Bone-Forming Potential in an Orthopedic Clinical Center in Brazil

In vitro-expanded bone marrow stromal cells (BMSCs) have long been proposed for the treatment of complex bone-related injuries because of their inherent potential to differentiate into multiple skeletal cell types, modulate inflammatory responses, and support angiogenesis. Although a wide variety of...

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Main Authors: Rhayra B. Dias, João A. M. Guimarães, Marco B. Cury, Leonardo R. Rocha, Elaine S. da Costa, Liebert P. Nogueira, Camila Hochman-Mendez, Anneliese Fortuna-Costa, Anna Karoline F. Silva, Karin S. Cunha, Sergio A. L. de Souza, Maria Eugênia L. Duarte, Rafaela C. Sartore, Danielle C. Bonfim
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2019/2608482
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http://dx.doi.org/10.1155/2019/2608482

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