Towards a comprehensive view of the pocketome universe-biological implications and algorithmic challenges.

With the availability of reliably predicted 3D-structures for essentially all known proteins, characterizing the entirety of compound-binding sites (binding pockets on proteins) has become a possibility. The aim of this study was to identify and analyze all compound-binding sites, i.e., the pocketom...

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Bibliographic Details
Main Authors: Hanne Zillmer, Dirk Walther
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-07-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1013298
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