Optochemical control over mRNA translation by photocaged phosphorodiamidate morpholino oligonucleotides in vivo
Abstract We developed an efficient, robust, and broadly applicable system for light-induced protein translation to control the production of proteins of interest and study their function. The method is based on the displacement of a single type of antisense morpholino from RNA by the uncaged guanidi...
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| Main Authors: | Katsiaryna Tarbashevich, Atanu Ghosh, Arnab Das, Debajyoti Kuilya, Swrajit Nath Sharma, Surajit Sinha, Erez Raz |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-58207-5 |
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