Repositioning of moxidectin: a promising approach in cutaneous leishmaniasis therapy

Repositioning of moxidectin: a promising approach in cutaneous leishmaniasis therapy

Cutaneous leishmaniasis presents a significant challenge to public health due to its diverse clinical manifestations, resistance development, and treatment-related adverse effects. Here, we examined the efficacy of ivermectin, moxidectin (MOX), afoxolaner, and permethrin against all stages of Leishm...

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Main Authors: Al Samra Lynn, El Nahas Mohamad, Mneimneh Ilham, Tokajian Sima, Nemer Georges, Sinno Aia, Rahy Kelven, Thoumi Sergio, Zibara Zahraa, El Khatib Ahmad, Sabbagh Dalal, Guillot Jacques, Karam Louna, Ali Lazo, Baghdadi Ruqaya, Al Khoury Charbel
Format: Article
Language:English
Published: EDP Sciences 2025-01-01
Series:Parasite
Subjects:
leishmania
leishmaniasis
moxidectin
drug repurposing
rna-seq
drug resistance
Online Access:https://www.parasite-journal.org/articles/parasite/full_html/2025/01/parasite240197/parasite240197.html
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https://www.parasite-journal.org/articles/parasite/full_html/2025/01/parasite240197/parasite240197.html

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