CREB binding protein (CREBBP): Structure-based perspectives for the development of clinical inhibitors

Acetylation is an essential process in biological processes. In tissues, protein acetylation occurs mainly at lysine (K) residues. The balance between acetylation and deacetylation is under the control of two enzyme families, histone acetyltransferase (HAT) and histone deacetylase (HDAC), respective...

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Bibliographic Details
Main Authors: Rongxing Liu, Jiaxin Li, Qing Nian, Gao Tu, Zhenqiang Wang, Rong Zhang, Guobing Li
Format: Article
Language:English
Published: Elsevier 2025-11-01
Series:Translational Oncology
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Online Access:http://www.sciencedirect.com/science/article/pii/S1936523325002384
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