Investigating the molecular mechanisms, drug prediction, and validation of CCNA2 and MAD2L1 in esophageal squamous cell carcinoma based on bioinformatics

Abstract Objective Aims to comprehensively investigate the expression patterns of CCNA2 and MAD2L1 in esophageal squamous cell carcinoma using bioinformatics methods. Methods Based on WGCNA analysis of gene mutation expression, methylation level distribution, mRNA expression and ESCC-related genes i...

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Bibliographic Details
Main Authors: Chenfan Guo, Pandeng Wang, Diemei Huang, Jianji Guo, Tao Liu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Medical Genomics
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Online Access:https://doi.org/10.1186/s12920-025-02173-w
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