Distinct composition of different types of Abeta plaques in the pathogenesis of Alzheimer’s disease and the role of neutrophil-derived myeloperoxidase

Distinct composition of different types of Abeta plaques in the pathogenesis of Alzheimer’s disease and the role of neutrophil-derived myeloperoxidase

Abstract Alzheimer’s disease (AD) is an age-related neurodegenerative disorder. Different types of Aβ plaques are likely to play distinct roles in the brains of patients with AD. In this study, through the combination of pathological techniques and analysis of the human brain database, we discovered...

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Bibliographic Details
Main Authors: Jianru Sun, Xiangqi Shao, Xue Wang, Xiang-sha Yin, Wenying Qiu, Xiaojing Qian, Fan Liu, Yongmei Chen, Chao Ma
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Molecular Brain
Subjects:
Amyloid plaques
Neutrophil granulocytes
MPO
ECog score
ABC score
Neuroimmune
Online Access:https://doi.org/10.1186/s13041-025-01226-6
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https://doi.org/10.1186/s13041-025-01226-6

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