Asiaticoside alleviates ferroptosis in myelodysplastic syndrome by activating SMAD7

Asiaticoside alleviates ferroptosis in myelodysplastic syndrome by activating SMAD7

Objective‍　‍To investigate the relationship of aberrant SMAD family member 7 (SMAD7) signaling pathway and ferroptosis in myelodysplastic syndromes (MDS) and evaluate the effect of asiaticoside (AC)-modulating SMAD7 up-regulation to suppress ferroptosis in MDS cell lines. Methods‍　‍Publicly availabl...

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Bibliographic Details
Main Authors: WANG Liye, CHANG Qing, DONG Tengteng
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2025-06-01
Series:陆军军医大学学报
Subjects:
smad7
asiaticoside
myelodysplastic syndrome
ferroptosis; oxidative stress
Online Access:https://aammt.tmmu.edu.cn/html/202503022.html
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