Insights into Keratinocyte and Immunologic Landscape in Cutaneous Graft-Versus-Host Disease through Single-Cell Transcriptomics

Insights into Keratinocyte and Immunologic Landscape in Cutaneous Graft-Versus-Host Disease through Single-Cell Transcriptomics

Cutaneous manifestations are the most common presenting sign of chronic graft-versus-host disease (GVHD), and the extent of cutaneous involvement is also highly correlated with prognosis. Very little is understood about the underlying pathogenesis underpinning injury at this location, especially the...

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Bibliographic Details
Main Authors: Amy J. Petty, Adela Rambi Cardones, Yingai Jane Jin, Vaibhav Jain, Emily Hocke, Harsh B. Pathak, Amrita Mitra, Simon G. Gregory, M. Angelica Selim, Jennifer Y. Zhang
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:JID Innovations
Subjects:
Cutaneous chronic GVHD
Graft-versus-host disease
Keratinocytes
M1 and M2 macrophages
T cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2667026725000293
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