Micrometer‐scale tPA beads amplify plasmin generation for enhanced thrombolytic therapy
Abstract Rapid restoration of blood flow is critical in treating acute ischemic stroke. Current thrombolytic therapies using tissue plasminogen activator (tPA) are limited by low recanalization rates and risks of off‐target bleeding. Here, we demonstrate that a remarkably simple adjustment—using mic...
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| Main Authors: | Matthew J. Osmond, Fabrice Dabertrand, Nidia Quillinan, Enming J. Su, Daniel A. Lawrence, David W. M. Marr, Keith B. Neeves |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-07-01
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| Series: | Bioengineering & Translational Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/btm2.70012 |
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