DeepGFT: identifying spatial domains in spatial transcriptomics of complex and 3D tissue using deep learning and graph Fourier transform

Abstract The rapid advancements in spatially resolved transcriptomics (SRT) enable the characterization of gene expressions while preserving spatial information. However, high dropout rates and noise hinder accurate spatial domain identification for understanding tissue architecture. We present Deep...

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Bibliographic Details
Main Authors: Shuli Sun, Jixin Liu, Guojun Li, Bingqiang Liu
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-025-03631-5
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