Mycobactin and clofazimine activity are negatively correlated in mycobacteria

Mycobactin and clofazimine activity are negatively correlated in mycobacteria

Clofazimine (CFZ) is an anti-leprosy drug shown to improve outcomes in treatment of multidrug-resistant tuberculosis (TB) and nontuberculous mycobacterial infections. Studies in Mycobacterium tuberculosis and Mycobacterium avium identified CFZ resistance mutations in the gene that encodes the MmpR5/...

Full description

Saved in:
Bibliographic Details
Main Authors: Martin I. Voskuil, Christopher R. Covey, Matthew J. Reichlen, Anushila Chatterjee, Breck A. Duerkop, Surendra Dawadi, Courtney C. Aldrich, Alexander Aaring
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Microbiology
Subjects:
clofazimine
mycobactin
Mycobacterium
iron
siderophore
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1539139/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2025.1539139/full

Similar Items