Current advances in the role of classical non‐homologous end joining in hematologic malignancies

Abstract Background Double‐strand breaks (DSBs) are universally acknowledged as the most detrimental type of DNA damage, and their effective repair primarily depends on the non‐homologous end joining (NHEJ) pathway. Such DSBs, which require NHEJ for resolution, can arise from intrinsic and extrinsic...

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Bibliographic Details
Main Authors: Pengcheng Liu, Zizhen Xu
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Clinical and Translational Discovery
Subjects:
Online Access:https://doi.org/10.1002/ctd2.70053
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