Targeting cholinergic dysfunction in Alzheimer’s disease: Development of next-generation galantamine derivatives
Alzheimer’s disease (AD) presents a significant and unmet medical need. Acetylcholinesterase (AChE) enzymes are key contributors to AD pathogenesis, instigating a cholinergic deficit and subsequent neurodegenerative progression, leading to neuronal loss and cognitive decline. This study leverages in...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-09-01
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| Series: | Journal of Genetic Engineering and Biotechnology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1687157X25000745 |
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