Heart ketone metabolism under acute ketone supplementation in ZDF rats, a type 2 diabetes heart failure model
Abstract Background In non-insulin-dependent, type 2, diabetes mellitus (T2D), glucose metabolism is compromised, and the heart loses its metabolic flexibility. The Zucker Diabetic Fatty rat (ZDF) model, which replicates the pathophysiology of T2D in patients, shows that as T2D progresses so does he...
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| Main Authors: | Etienne Croteau, Gabriel Richard, Patrick Prud’Homme, Etienne Rousseau, Stephen C. Cunnane, Véronique Dumulon-Perreault, Otman Sarrhini, Serge Phoenix, Sébastien Tremblay, Brigitte Guérin, Roger Lecomte |
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| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2025-03-01
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| Series: | EJNMMI Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13550-025-01215-9 |
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