A functional interleukin-4 homolog is encoded in the genome of infectious laryngotracheitis virus: Unveiling a novel virulence factor.

A functional interleukin-4 homolog is encoded in the genome of infectious laryngotracheitis virus: Unveiling a novel virulence factor.

Herpesviruses have evolved numerous immune evasion tactics, persisting within their hosts through self-perpetuating strategies. One such tactic involves acquiring functional copies of host genes encoding cytokines such as IL-6 (HHV-8), IL-10 (HHV-4, HHV-5), and IL-17 (SaHV-2). These viral mimics, or...

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Bibliographic Details
Main Authors: Jeremy D Volkening, Stephen J Spatz, Maricarmen Garcia, Teresa A Ross, Daniel A Maekawa, Kenneth S Rosenthal, Ana C Zamora, April Skipper, Julia R Blakey, Rashan Paudel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1013219
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https://doi.org/10.1371/journal.ppat.1013219

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