Investigation of Zur-regulated metal transport systems reveals an unexpected role of pyochelin in zinc homeostasis

Investigation of Zur-regulated metal transport systems reveals an unexpected role of pyochelin in zinc homeostasis

ABSTRACT Limiting the availability of transition metals at infection sites serves as a critical defense mechanism employed by the innate immune system to combat microbial infections. Pseudomonas aeruginosa exhibits a remarkable ability to thrive in zinc-deficient environments, facilitated by intrica...

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Main Authors: Valerio Secli, Emma Michetti, Francesca Pacello, Federico Iacovelli, Mattia Falconi, Maria Luisa Astolfi, Daniela Visaggio, Paolo Visca, Serena Ammendola, Andrea Battistoni
Format: Article
Language:English
Published: American Society for Microbiology 2024-10-01
Series:mBio
Subjects:
metal transport
metallophore
zinc transport
iron transport
Pseudomonas aeruginosa
siderophores
Online Access:https://journals.asm.org/doi/10.1128/mbio.02395-24
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https://journals.asm.org/doi/10.1128/mbio.02395-24

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