Mechanism of hedysari radix praeparata cum melle and curcumae rhizoma herb pair in colitis-associated colorectal cancer through the MAPK/NF-κB signaling pathway: an investigation in vivo and in vitro

Mechanism of hedysari radix praeparata cum melle and curcumae rhizoma herb pair in colitis-associated colorectal cancer through the MAPK/NF-κB signaling pathway: an investigation in vivo and in vitro

IntroductionAstragali Radix (AR) - Curcumae Rhizoma (vinegar processed, CR) herb pair was recorded in ‘YIXUE ZHONGZHONG CANXILU’ to treat colitis-associated colorectal cancer (CAC). Hedysari Radix (HR) was categorized under the AR entry in ‘SHENNONG BENCAO JING’. HR is still an alternative to AR pai...

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Bibliographic Details
Main Authors: Ting Liu, Yugui Zhang, Feiyun Gao, Zhuanhong Zhang, Maomao Wang, Cui Ma, Yanjun Wang, Dingcai Ma, Zhe Wang, Xingke Yan, Yuefeng Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Chemistry
Subjects:
hedysari radix praeparata cum melle-curcumae rhizoma (vinegar processed)
colitis-associated colorectal cancer
drug-containing intestinal absorption solution
network analysis
intestinal permeability
MAPK/NF-kB signaling pathways
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2025.1551722/full
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https://www.frontiersin.org/articles/10.3389/fchem.2025.1551722/full

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