Development and Evaluation of a Cost-Effective, Carbon-Based, Extended-Release Febuxostat Tablet

This study outlines the development of a cost-effective, extended-release febuxostat (FEB) tablet using activated charcoal as an adsorbent to enhance drug release. FEB, a BCS Class II drug, presents formulation challenges due to low solubility and high lipophilicity. We evaluated eight formulations...

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Bibliographic Details
Main Authors: Israa Hamid Al-Ani, Mohammad Hailat, Dina J. Mohammed, Sina Mahmoud Matalqah, Alaa Azeez Abu Dayah, Bashar J. M. Majeed, Riad Awad, Lorena Filip, Wael Abu Dayyih
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/29/19/4629
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