Nongenomic Mechanisms of PTEN Regulation
A large amount of data supports the view that PTEN is a bona fide tumor suppressor gene. However, recent evidence suggests that derailment of cellular localization and expression levels of functional nonmutated PTEN is a determining force in inducing abnormal cellular and tissue outcomes. As the cel...
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Main Authors: | Jimmie E. Fata, Shawon Debnath, Edmund C. Jenkins, Marcia V. Fournier |
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Format: | Article |
Language: | English |
Published: |
Wiley
2012-01-01
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Series: | International Journal of Cell Biology |
Online Access: | http://dx.doi.org/10.1155/2012/379685 |
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