Enhanced nattokinase production by Bacillus subtilis from glycerol and okara: optimization of culture medium via response surface methodology
IntroductionNattokinase is an alkaline serine protease with potent thrombolytic activity. Due to its safety profile, low cost, and ease of oral administration, it has gained significant attention for therapeutic applications. To meet the demand for cost-effective production of nattokinase via fermen...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2025.1577292/full |
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