Fluorescence study of freeze-drying as a method for support the interactions between hyaluronan and hydrophobic species.

A freeze-drying method enabling solubilization of hydrophobic species in aqueous solutions of native hyaluronan is described. The method is based on opening the access to supposed hydrophobic patches on hyaluronan by disturbing its massive hydration shell. Hydrophobic and/or polarity-sensitive fluor...

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Bibliographic Details
Main Authors: Petra Michalicová, Filip Mravec, Miloslav Pekař
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0184558&type=printable
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