Ferroptosis as a potential molecular mechanism of bipolar disorder

Abstract The unclear pathogenesis of bipolar disorder (BD) poses a challenge, especially with the striking rates of comorbid medical and psychiatric disorders, treatment resistance, and premature mortality in the absence of a specific diagnostic marker. We put forward the hypothesis of ferroptosis,...

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Bibliographic Details
Main Authors: Asmaa Yehia, Lindsay M. Melhuish Beaupre, Man Choi Ho, Joanna M. Biernnacka, Mark A. Frye, Osama A. Abulseoud
Format: Article
Language:English
Published: Nature Publishing Group 2025-06-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-025-03429-w
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