Persistent articular infection and host reactive response contribute to Brucella-induced spondyloarthritis in SKG mice

ABSTRACT Brucellosis, one of the most prevalent zoonotic diseases worldwide, often results in osteoarticular complications including large joint and axial arthritis mimicking spondyloarthritis. To model this chronic manifestation, we infected autoimmunity-prone SKG mice containing a mutation in the...

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Bibliographic Details
Main Authors: Jerome S. Harms, Michael Lasarev, Thomas Warner, Sergio Costa Oliveira, Judith A. Smith
Format: Article
Language:English
Published: American Society for Microbiology 2025-06-01
Series:mBio
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Online Access:https://journals.asm.org/doi/10.1128/mbio.00542-25
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