Comparison of efficacy and adverse effects of CD19/20 CART versus CD19 single-target CART in R/R DLBCL: a single-center retrospective study

Comparison of efficacy and adverse effects of CD19/20 CART versus CD19 single-target CART in R/R DLBCL: a single-center retrospective study

PurposeCD19 Chimeric Antigen Receptor T-cell therapy (CART) represents a groundbreaking approach in the treatment of relapsed or refractory diffuse large B-cell lymphoma (R/R DLBCL). However, a subset of patients fails to achieve optimal outcomes with CD19-targeted CAR T-cells alone. To address thes...

Full description

Saved in:
Bibliographic Details
Main Authors: Bin Xue, Yifan Liu, Bing Li, Yan Lu, Lili Zhou, Shiguang Ye, Huina Lu, Xiu Luo, Aibin Liang, Ping Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
CAR-T
lymphoma
dual-target
CD19
CD19/20
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1582944/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2025.1582944/full

Similar Items