Analysis of Key Differential Metabolites in Intervertebral Disc Degeneration Based on Untargeted Metabolomics

Analysis of Key Differential Metabolites in Intervertebral Disc Degeneration Based on Untargeted Metabolomics

ABSTRACT Background Intervertebral disc degeneration disease (IVDD) is a prevalent orthopedic condition that causes chronic lower back pain, imposing a substantial economic burden on patients and society. Despite its high incidence, the pathophysiological mechanisms of IVDD remain incompletely under...

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Main Authors: Daqian Zhou, Xingrui Zhang, Jiale Lv, Yongliang Mei, Yingjin Luo, Fengjiang Li, Zongchao Liu
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:JOR Spine
Subjects:
intervertebral disc degeneration
IVDD
metabolic marker
nontargeted metabolomics
UHPLC‐MS
Online Access:https://doi.org/10.1002/jsp2.70032
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https://doi.org/10.1002/jsp2.70032

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