Epsin3 promotes non-small cell lung cancer progression via modulating EGFR stability

Epsin3 promotes non-small cell lung cancer progression via modulating EGFR stability

Abstract Background The abnormal expression and overactivation of the epidermal growth factor receptor (EGFR), a typical cancer marker for non-small cell lung cancer (NSCLC), are closely related to the tumorigenesis and progression of NSCLC. However, the endocytosis mechanism of EGFR in lung cancer...

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Bibliographic Details
Main Authors: Huiling Su, Jie Shen, Chenzi Gao, Yue Zhao, Wanyu Deng, Bo Qin, Xin Zhang, Juan Lai, Qian Wang, Jie Dou, Min Guo
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Cell & Bioscience
Subjects:
Non-small cell lung cancer
Epsin3
EGFR
TKI resistance
Online Access:https://doi.org/10.1186/s13578-025-01358-1
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https://doi.org/10.1186/s13578-025-01358-1

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