Assessment of the plasticity of dry granulated particles (mini-tablets) and its relationship to their tabletability

Mini-tablets of different proportions of α-lactose monohydrate (LAC) and microcrystalline cellulose (MCC) were prepared by uniaxial compaction and served as surrogate granules. The inverted Adams coefficient i.e., α−1 was derived from bulk mini-tablet compression data and used as an indication of gr...

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Bibliographic Details
Main Authors: Maryam Tofiq, Göran Alderborn, Josefina Nordström, Ann-Sofie Persson
Format: Article
Language:English
Published: Elsevier 2025-12-01
Series:International Journal of Pharmaceutics: X
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590156725000362
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